Alisa and her former FBI partner, Joel, learn of a government plan to capture them in order to steal and analyze their vampire blood for the purpose of duplicating it, and when Joel is caught, Alisa risks her life to free him.

This third volume follows directly from the events recounted in The Last Vampire 2: Black Blood. Sita regains consciousness and finds herself surrounded by the police, S.W.A.T., and higher government groups. Realizing that she cannot allow Eddie Fender's blood to fall into the wrong hands, Sita comes to the conclusion that she must burn down the entire house.